Journal article
Antiseptic mouthwash against pharyngeal Neisseria gonorrhoeae: A randomised controlled trial and an in vitro study
EPF Chow, BP Howden, S Walker, D Lee, CS Bradshaw, MY Chen, A Snow, S Cook, G Fehler, CK Fairley
Sexually Transmitted Infections | BMJ PUBLISHING GROUP | Published : 2017
Abstract
Background Gonorrhoea is increasing among men who have sex with men (MSM). We aimed to determine whether Listerine, a commercial mouthwash product, has an inhibitory effect against Neisseria gonorrhoeae in a randomised controlled trial (RCT) and an in vitro study, and therefore may be a potentially useful agent for gonorrhoea control. Methods In vitro: a suspension of ∼10 8 colony forming units per mL (CFU/mL) of N. gonorrhoeae was added to a serial of dilutions (up to 1:32) of alcohol-containing Listerine mouthwashes (Cool Mint and Total Care) for 1min. A 10μL aliquot was spread over the surface of a gonococcal agar plate and the number of N. gonorrhoeae colonies present at each dilution wa..
View full abstractGrants
Awarded by Australian National Health and Medical Research Council (NHMRC)
Awarded by Early Career Fellowships from the Australian NHMRC
Funding Acknowledgements
This work was supported by the Australian National Health and Medical Research Council (NHMRC) programme grant (grant number 568971). EPFC is supported by the Early Career Fellowships from the Australian NHMRC (number 1091226).